Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Pharmacology

Agonist

A ligand that binds a receptor and produces a response. Full agonists produce the maximal response the system can give; partial agonists produce less at full occupancy.

Document identifier
CEI-GT-102
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Agonist

§1.2Category

Pharmacology — Terms describing how a compound acts and how the body handles it.

§1.3Related terms

  • Partial agonist — A ligand producing a submaximal response at full receptor occupancy. May behave as an antagonist in the presence of a full agonist.
  • Antagonist — A ligand that binds a receptor without producing a response and prevents an agonist from doing so.
Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.