Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Working tools

Calculators

Five calculators covering the arithmetic that most often goes wrong when a certificate is read or a lyophilisate is reconstituted.

§1The calculators

Reconstitution and insulin units

Concentration, injection volume, syringe units and doses per vial, with a statement of where graduation error becomes a large fraction of the dose.

Incretin dose equivalence

Illustrative equivalence anchored on placebo-subtracted weight change at the highest dose evaluated in each pivotal programme. Refuses to extrapolate past the ceiling.

Purity against peptide content

The arithmetic of delivered peptide mass, and whether the declared fractions permit a mass balance to be closed.

Certificate minimum-data checker

Score a certificate against the Institute’s minimum data standard, with critical fields weighted separately from recommended ones.

Storage and in-use stability lookup

What the Institute has assessed for a compound at a given state and temperature, and what it declines to claim.

§2Standing terms

Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.