Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Pharmacology

Bioavailability

The fraction of an administered dose reaching the systemic circulation unchanged. Low and variable for orally administered peptides, which is the constraint every oral peptide presentation exists to…

Document identifier
CEI-GT-108
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Bioavailability

§1.2Category

Pharmacology — Terms describing how a compound acts and how the body handles it.

§1.3Related terms

  • Permeation enhancer — An excipient that increases absorption across a mucosal surface. In the oral peptide presentation in this document set it transiently raises local pH and increases…
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