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Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Pharmacology

Dual agonist

A single molecule engineered to activate two receptors. In this document set the combinations of interest are GIP with GLP-1, and glucagon with GLP-1, which produce different profiles.

Document identifier
CEI-GT-120
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Dual agonist

§1.1Also known as

Co-agonist

§1.2Category

Pharmacology — Terms describing how a compound acts and how the body handles it.

§1.3Related terms

  • Triple agonist — A single molecule activating three receptors, in this set GIP, GLP-1 and glucagon. The glucagon component contributes an energy-expenditure effect and a hepatic effect…
  • GLP-1 receptor agonist — A compound activating the glucagon-like peptide-1 receptor, a class B G protein-coupled receptor signalling principally through Gαs. Effects include glucose-dependent…
Compound Evidence Institute · CEI-GT-120 · https://compoundevidence.com/glossary/dual-agonist/ · retrieved 30 July 2026
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