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Document set current to 30 July 2026
Defined term · Analytical chemistry

Forced degradation

Deliberate exposure of a sample to heat, light, acid, base and oxidant to generate degradation products against which a method’s specificity is demonstrated.

Document identifier
CEI-GT-134
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Forced degradation

§1.1Also known as

Stress testing

§1.2Category

Analytical chemistry — Terms describing the determination of identity, purity, content and quality.

§1.3Related terms

  • Stability-indicating — A property of a method that separates the intact compound from its degradation products, demonstrated by forced-degradation study. A purity method that is not…
Compound Evidence Institute · CEI-GT-134 · https://compoundevidence.com/glossary/forced-degradation/ · retrieved 30 July 2026
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