Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Evidence assessment

High certainty

The Institute is confident that the true effect lies close to the estimate. Further research is very unlikely to change confidence in the estimate. A high rating is not a claim of proof and does not…

Document identifier
CEI-GT-002
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1High certainty

§1.2Category

Evidence assessment — Terms describing how the Institute judges and reports the strength of evidence.

§1.3Related terms

  • Certainty of evidence — The Institute’s judgement of the extent to which an effect estimate is adequate to support a conclusion. Reported at one of four levels: high, moderate, low or very low…
Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.