Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Evidence assessment

Low certainty

Confidence in the effect estimate is limited and the true effect may be substantially different. The Institute states in each case whether the limitation arises from conflicting evidence or from thin…

Document identifier
CEI-GT-004
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Low certainty

§1.2Category

Evidence assessment — Terms describing how the Institute judges and reports the strength of evidence.

§1.3Related terms

  • Certainty of evidence — The Institute’s judgement of the extent to which an effect estimate is adequate to support a conclusion. Reported at one of four levels: high, moderate, low or very low…
  • Absence of evidence — A state in which no study adequate to answer a question has been identified. The Institute records an absence of evidence as distinct from evidence of absence: the first…
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