Defined term · Analytical chemistry
Mass balance
The sum of peptide content, water content and counter-ion content, which should approach one hundred per cent. A certificate that does not permit a mass balance to be closed is incomplete under the…
§1Mass balance
§1.2Category
Analytical chemistry — Terms describing the determination of identity, purity, content and quality.
§1.3Related terms
- Peptide content — The mass fraction of a lyophilisate that is peptide, the remainder being water, counter-ion and residual solvent. Determined by amino-acid analysis or nitrogen…
- Counter-ion — The ion paired with a charged peptide, most often trifluoroacetate or acetate from purification. Can constitute a substantial fraction of the mass of a basic peptide and…
Compound Evidence Institute · CEI-GT-137 · https://compoundevidence.com/glossary/mass-balance/ · retrieved 30 July 2026