Defined term · Evidence assessment
Protocol registration
The recording of a review question, eligibility criteria and analysis plan before the search is executed. Registration is what makes a subsequent change identifiable as post hoc rather than planned.
§1Protocol registration
§1.2Category
Evidence assessment — Terms describing how the Institute judges and reports the strength of evidence.
§1.3Related terms
- PICO — The four elements that define a review question: population, intervention, comparator and outcome. The Institute registers a PICO frame before searching and records any…
- Amendment log — The record attached to every Institute synthesis listing each change made after protocol registration, when it was made, and why. A change that is not in the log did not…
Compound Evidence Institute · CEI-GT-021 · https://compoundevidence.com/glossary/protocol-registration/ · retrieved 30 July 2026