Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Analytical chemistry

Trifluoroacetate

The counter-ion most commonly introduced by reverse-phase purification with trifluoroacetic acid. Quantified by ion chromatography or fluorine nuclear magnetic resonance, and reported on few…

Document identifier
CEI-GT-139
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Trifluoroacetate

§1.1Also known as

TFA

§1.2Category

Analytical chemistry — Terms describing the determination of identity, purity, content and quality.

§1.3Related terms

  • Counter-ion — The ion paired with a charged peptide, most often trifluoroacetate or acetate from purification. Can constitute a substantial fraction of the mass of a basic peptide and…
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