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Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Outcomes and endpoints

Clinical outcome

An outcome a person would notice or care about directly: death, an event, a symptom, a function. Distinguished throughout the document set from a surrogate.

Document identifier
CEI-GT-091
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Clinical outcome

§1.1Also known as

Patient-important outcome

§1.2Category

Outcomes and endpoints — Terms describing what a study measures and what the measurement supports.

§1.3Related terms

  • Surrogate outcome — A measurement substituted for a clinical outcome on the assumption that a change in one predicts a change in the other. Validation of that assumption requires…
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