Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
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Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Trial design and conduct

Estimand

A precise statement of the quantity a trial is estimating, including how intercurrent events such as discontinuation or rescue therapy are handled. Two trials reporting the same endpoint under…

Document identifier
CEI-GT-053
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Estimand

§1.2Category

Trial design and conduct — Terms describing how a clinical study is constructed and run.

§1.3Related terms

  • Intention to treat — Analysis of participants in the group to which they were randomised, regardless of the treatment they received. Preserves the comparison randomisation created and…
  • Intercurrent event — An event occurring after randomisation that affects the interpretation of the outcome, such as treatment discontinuation, rescue medication or death. The strategy for…
Compound Evidence Institute · CEI-GT-053 · https://compoundevidence.com/glossary/estimand/ · retrieved 30 July 2026
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