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Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Pharmacology

Tachyphylaxis

Rapid attenuation of response with repeated administration. Documented for several growth-hormone secretagogues and material to any claim about sustained effect.

Document identifier
CEI-GT-115
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Tachyphylaxis

§1.2Category

Pharmacology — Terms describing how a compound acts and how the body handles it.

§1.3Related terms

  • Desensitisation — Reduction in receptor responsiveness following sustained stimulation, often through receptor internalisation. The pharmacological reason that non-pulsatile…
Compound Evidence Institute · CEI-GT-115 · https://compoundevidence.com/glossary/tachyphylaxis/ · retrieved 30 July 2026
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