Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Indication assessment · §4

HIV-associated lipodystrophy and excess visceral adiposity — compounds assessed

The 1 compound the Institute assesses in hiv-associated lipodystrophy and excess visceral adiposity.

Document identifier
CEI-IN-20/4
Series
Indication assessment
Version
2.3
Published
05 Nov 2024
Last reviewed
05 Nov 2024
Next review
05 Nov 2026
Identifier
10.71829/cei.ind.20
Certainty
Not rated
Cycle
2024 Q4
ICD-11
5C71
Category
Endocrine

§4Compounds assessed

Compounds the Institute assesses in this indication, with the class of each and its overall certainty. A compound appears here whether or not the evidence supports its use, because recording that a compound has been studied and found wanting is as much part of the assessment as recording that one has not.

  • Growth-hormone-releasing hormone analogue2 contributing trialsfull monograph

    Visceral adipose tissue reduced by 15.2 % versus 5.0 % increase with placebo at 26 weeks — Two pivotal trials in HIV-associated lipodystrophy with computed-tomography endpoints. Downgraded for indirectness when applied to any population outside that…

    Moderate

References cited on this page

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. Falutz J, Allas S, Blot K, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S. Metabolic effects of a growth hormone-releasing factor in patients with HIV. New England Journal of Medicine 2007;357(23):2359–2370. doi:10.1056/NEJMoa072375 · PMID 18052660

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

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