Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Compound monograph · §10

MOTS-c — references and citing documents

The full reference list for this monograph, and every Institute document that draws on it.

Document identifier
CEI-MN-043/10
Series
Compound monograph
Version
1.0
Published
20 May 2024
Last reviewed
20 Aug 2025
Next review
20 Aug 2027
Identifier
10.71829/cei.mono.43
Certainty
Very low
Cycle
2024 Q2

§10References

Every reference the monograph relies on is listed below in order of first citation across the document. Identifiers are reproduced only where the Institute holds them; where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed one.

This monograph cites 4 sources[1,2,3,4].

Table 9. Bibliographic records for the sources cited by this monograph. Each links to its record page, which lists every Institute document citing it.

§11Related Institute documents

Table 10. Institute documents that draw on, or are drawn on by, this monograph.

SeriesCountDocuments
Trial abstracts0
Evidence syntheses1Mitochondria-targeted peptides in bioenergetic disorders
Comment periods1Draft monograph: MOTS-c
Indication assessments4Type 2 diabetes · Obesity · Ageing · Mitochondrial disease

Numbered reference list

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H, Hevener AL, de Cabo R, Cohen P. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism 2015;21(3):443–454. doi:10.1016/j.cmet.2015.02.009 · PMID 25738459
  2. D’Hondt M, Bracke N, Taevernier L, Gevaert B, Verbeke F, Wynendaele E, De Spiegeleer B. Related impurities in peptide medicines. Journal of Pharmaceutical and Biomedical Analysis 2014;101:2–30. doi:10.1016/j.jpba.2014.06.012 · PMID 25044089
  3. Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharmaceutical Research 2010;27(4):544–575. doi:10.1007/s11095-009-0045-6 · PMID 20143256
  4. Bhattacharyya S, Wang J, Kaplan RM. Quality of peptide products obtained from unregulated online suppliers: an analytical survey. Journal of Pharmaceutical Sciences 2024;113(4):1102–1110. doi:10.1016/j.xphs.2023.11.021 Cited by the Institute as an indicative analytical survey; sample frame was not random.

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

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