Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
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Trial abstracts — page 3

700 structured trial abstracts. Each is one document in five parts: abstract, design and population, results, certainty assessment and citing documents.

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Trial records

700 documents · page 3 of 30

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
STEP-TEENSSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2012022Moderate
SURMOUNT-1TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2,5392022High
SURPASS-5TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled4752022High
AMPLITUDE-OExenatidePhase 3ReportedEvent-driven cardiovascular outcome trial4,0762021Moderate
CAGRI-PH2-DOSEFINDCagrilintidePhase 2ReportedDose-finding7062021Moderate
STEP-1SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,9612021High
STEP-2SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,2102021High
STEP-3SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6112021High
STEP-4SemaglutidePhase 3ReportedRandomised withdrawal8032021High
SURPASS-1TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled4782021High
SURPASS-2TirzepatidePhase 3ReportedRandomised, double-blind, active-controlled1,8792021High
SURPASS-3TirzepatidePhase 3ReportedRandomised, open-label, active-controlled1,4442021High
SURPASS-4TirzepatidePhase 3ReportedRandomised, open-label, active-controlled2,0022021High
AWARD-11DulaglutidePhase 3ReportedRandomised, double-blind, active-controlled1,8422020High
SCALE-TEENSLiraglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2512020Moderate
TED-PAEDIATRICTeduglutidePhase 3ReportedSingle-arm open-label592020Moderate
ELAM-PH2-HFPEFSS-31 (elamipretide)Phase 2ReportedRandomised, double-blind, placebo-controlled712019Low
PIONEER-1Semaglutide, oralPhase 3ReportedRandomised, double-blind, placebo-controlled7032019High
PIONEER-6Semaglutide, oralPhase 3ReportedEvent-driven cardiovascular outcome trial3,1832019High
RECONNECT-301PT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled6262019Moderate
RECONNECT-302PT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled6302019Moderate
REWINDDulaglutidePhase 3ReportedEvent-driven cardiovascular outcome trial9,9012019High
TESA-NAFLD-PH2TesamorelinPhase 2ReportedRandomised, double-blind, placebo-controlled612019Low
AWARD-7DulaglutidePhase 3ReportedRandomised, open-label, active-controlled5762018Low

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