Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Development programme

TRIUMPH — retatrutide

The phase 3 programme for the triple GIP, GLP-1 and glucagon receptor agonist retatrutide. At the assessment date the programme had not reported a completed phase 3 result, and the Institute grades retatrutide outcomes on phase 2 evidence only.

The phase 3 programme for the triple GIP, GLP-1 and glucagon receptor agonist retatrutide. At the assessment date the programme had not reported a completed phase 3 result, and the Institute grades retatrutide outcomes on phase 2 evidence only.

Sponsor class: Manufacturer-sponsored. First record: 2022.

Showing 0 records on this page

Records in this programme

17 documents

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
TRIUMPH-1RetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledNot rated
TRIUMPH-2RetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledNot rated
TRIUMPH-3RetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledNot rated
TRIUMPH-4RetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledNot rated
TRIUMPH-OSARetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledNot rated
TRIUMPH-1-DDIprogramme recordRetatrutidePhase 1OngoingRandomised crossoverVery low
TRIUMPH-1-PKprogramme recordRetatrutidePhase 1OngoingPhase 1 ascending doseVery low
TRIUMPH-1-RENAL-IMPprogramme recordRetatrutidePhase 1OngoingPhase 1 ascending doseVery low
TRIUMPH-2-BODY-COMPprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-2-QOLprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-2-REGIONAL-CNprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-2-REGIONAL-JPprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-3-BIOMARKERprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-3-OLEprogramme recordRetatrutidePhase 3OngoingSingle-arm open-labelVery low
TRIUMPH-4-BODY-COMPprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-4-REGIONAL-JPprogramme recordRetatrutidePhase 3OngoingRandomised, double-blind, placebo-controlledVery low
TRIUMPH-OSA-OLEprogramme recordRetatrutidePhase 3OngoingSingle-arm open-labelVery low
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