Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Methodology|Interests|Funding|Corrections
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Development programme

ACHIEVE — orforglipron in type 2 diabetes

The phase 3 glycaemic programme for orforglipron across background therapies and as monotherapy.

The phase 3 glycaemic programme for orforglipron across background therapies and as monotherapy.

Sponsor class: Manufacturer-sponsored. First record: 2023.

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Records in this programme

9 documents

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
ACHIEVE-1OrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled—2025Not rated
ACHIEVE-2OrforglipronPhase 3ReportedRandomised, double-blind, active-controlled—2025Not rated
ACHIEVE-1-BODY-COMPprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled—2025Very low
ACHIEVE-1-QOLprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled—2025Very low
ACHIEVE-1-REGIONAL-JPprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled—2025Very low
ACHIEVE-2-ADHERENCEprogramme recordOrforglipronPhase 3ReportedObservational—2025Very low
ACHIEVE-2-BIOMARKERprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled—2025Very low
ACHIEVE-2-ELDERLYprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled—2025Very low
ACHIEVE-2-OLEprogramme recordOrforglipronPhase 3ReportedSingle-arm open-label—2025Very low
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