Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Methodology|Interests|Funding|Corrections
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Development programme

EXSCEL — exenatide extended release cardiovascular outcomes

A large pragmatic cardiovascular outcome trial whose primary result did not reach the conventional significance threshold despite a point estimate favouring treatment.

A large pragmatic cardiovascular outcome trial whose primary result did not reach the conventional significance threshold despite a point estimate favouring treatment.

Sponsor class: Manufacturer-sponsored. First record: 2010.

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Records in this programme

4 documents

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
EXSCELExenatidePhase 3ReportedEvent-driven cardiovascular outcome trial14,7522017High
EXSCEL-BODY-COMPprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled—2017Very low
EXSCEL-QOLprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled—2017Very low
EXSCEL-REGIONAL-CNprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled—2017Very low
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