Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Development programme

RECONNECT — bremelanotide (PT-141)

The pivotal programme for the melanocortin receptor agonist bremelanotide in hypoactive sexual desire disorder in premenopausal women.

The pivotal programme for the melanocortin receptor agonist bremelanotide in hypoactive sexual desire disorder in premenopausal women.

Sponsor class: Manufacturer-sponsored. First record: 2014.

Showing 0 records on this page

Records in this programme

11 documents

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
RECONNECT-301PT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled6262019Moderate
RECONNECT-302PT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled6302019Moderate
RECONNECT-301-ADHERENCEprogramme recordPT-141 (bremelanotide)Phase 3ReportedObservational2019Very low
RECONNECT-301-BODY-COMPprogramme recordPT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled2019Very low
RECONNECT-301-QOLprogramme recordPT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled2019Very low
RECONNECT-301-REGIONAL-CNprogramme recordPT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled2019Very low
RECONNECT-301-REGIONAL-JPprogramme recordPT-141 (bremelanotide)Phase 3ReportedRandomised, double-blind, placebo-controlled2019Very low
RECONNECT-302-DDIprogramme recordPT-141 (bremelanotide)Phase 1ReportedRandomised crossover2019Very low
RECONNECT-302-HEPATIC-IMPprogramme recordPT-141 (bremelanotide)Phase 1ReportedPhase 1 ascending dose2019Very low
RECONNECT-302-PKprogramme recordPT-141 (bremelanotide)Phase 1ReportedPhase 1 ascending dose2019Very low
RECONNECT-302-RENAL-IMPprogramme recordPT-141 (bremelanotide)Phase 1ReportedPhase 1 ascending dose2019Very low
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