Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Reported trial records — page 3

644 records with the status reported.

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Records

644 documents · page 3 of 27

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
REDEFINE-2-BIOMARKERprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
SOUL-DDIprogramme recordSemaglutide, oralPhase 1ReportedRandomised crossover2025Very low
STRIDE-REGIONAL-JPprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
GLORY-1-REGIONAL-JPprogramme recordMazdutidePhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
SURPASS-CVOT-DDIprogramme recordTirzepatidePhase 1ReportedRandomised crossover2025Very low
ACHIEVE-2-BIOMARKERprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
REDEFINE-2-ADHERENCEprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedObservational2025Very low
SOUL-HEPATIC-IMPprogramme recordSemaglutide, oralPhase 1ReportedPhase 1 ascending dose2025Very low
ESSENCE-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2025Very low
GLORY-1-OLEprogramme recordMazdutidePhase 3ReportedSingle-arm open-label2025Very low
ECNO-PH3-CN-T2D-REGIONAL-CNprogramme recordEcnoglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
STEP-HFpEF-DMSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6162024Moderate
FLOWSemaglutidePhase 3ReportedEvent-driven kidney outcome trial3,5332024High
SURMOUNT-4TirzepatidePhase 3ReportedRandomised withdrawal6702024High
SURMOUNT-OSA-1TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2024High
SURMOUNT-OSA-2TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2024High
SUMMITTirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled7312024Moderate
SURVO-PH2-OBESITYSurvodutidePhase 2ReportedRandomised, double-blind, placebo-controlled3872024Moderate
SURVO-PH2-MASHSurvodutidePhase 2ReportedRandomised, double-blind, placebo-controlled2952024Low
SYNERGY-NASHTirzepatidePhase 2ReportedRandomised, double-blind, placebo-controlled1902024Low
PETRE-PH1BPetrelintidePhase 1ReportedPhase 1 ascending dose2024Low
REIMAGINE-1AmycretinPhase 1ReportedPhase 1 ascending dose1252024Low
DREAMS-1MazdutidePhase 3ReportedRandomised, double-blind, placebo-controlled3192024Moderate
DREAMS-2MazdutidePhase 3ReportedRandomised, double-blind, placebo-controlled7312024Moderate

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